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Public Health England has stated that vaping is at least 95% less harmful than smoking

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Wang M, Gu D, Zhang Z, Zhou J, Zhang Z (2009) XPD polymorphisms, cigarette smoking, and bladder cancer risk: a meta-analysis

As a general rule, light to moderate users can expect: Around 46 days of use from a 9,000-puff device About a week to 10 days from a 15,000-puff Geek Bar Pulse Up to two weeks or more from 25,000-puff devices like the Skyview or Pulse X Of course, real-world results vary